Elastosis during airway wall remodeling explains multiple co-existing instability patterns
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چکیده
منابع مشابه
Elastosis during airway wall remodeling explains multiple co-existing instability patterns.
Living structures can undergo morphological changes in response to growth and alterations in microstructural properties in response to remodeling. From a biological perspective, airway wall inflammation and airway elastosis are classical hallmarks of growth and remodeling during chronic lung disease. From a mechanical point of view, growth and remodeling trigger mechanical instabilities that re...
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When airways narrow, either through the action of smooth muscle shortening or during forced expiration, the lung parenchyma is locally distorted and provides an increased peribronchial stress that resists the narrowing. Although this interdependence has been well studied, the quantitative significance of airway remodeling to interdependence has not been elucidated. We have used an improved comp...
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ژورنال
عنوان ژورنال: Journal of Theoretical Biology
سال: 2016
ISSN: 0022-5193
DOI: 10.1016/j.jtbi.2016.05.022